1. Stone formation occurs most commonly in the submandibular gland for several reasons. 2. The submandibular gland 's highly active acini account for most of the salivary volume. 3. The secretory acinar cells of the submandibular gland have distinct functions. 4. EGF has since been found in many human tissues including submandibular gland , parotid gland. 5. The submandibular gland saliva is also relatively alkaline and mucous. 6. Examples of where it can be found include the parotid gland and submandibular gland . 7. The ImSAIDs were discovered by scientists evaluating biological properties of the submandibular gland and saliva. 8. Rarely, removal of the submandibular gland may become necessary in cases of recurrent stone formation. 9. When a worker ant's leg is grasped, it suicidally expels the contents of its hypertrophied submandibular glands , 10. The facial nerve also supplies parasympathetic fibers to the submandibular gland and sublingual glands via chorda tympani.